Physical Fusion UV Defense SPF 50
SKINCEUTICALS
A patented and unique anti-aging cream to nourish dry skin & rebuild the skin's moisture barrier. U.S. Patent No. 10,137,073. Skinceutical's Triple Lipid Restore 2:4:2 is an anti-aging cream that contains the patented lipid ratio of 2% pure ceramides 1 and 3, 4% natural cholesterol, and 2% fatty acids, which is proven to nourish dry skin and reverse signs of aging. Optimal for anti-aging skincare, this lipid correction cream contains the first 2:4:2 cholesterol-dominant ratio to help restore the skin's external moisture barrier and support natural self-repair. As one of our best anti aging creams, Triple Lipid Restore 2:4:2 potently nourishes aging skin which leads to improvements in the visible appearance of skin smoothness, laxity, pores, and overall radiance.
First, apply a small amount between fingertips. Warm and melt the cream in circular motions. Apply once or twice daily to face, neck, and chest areas. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.
• Replenishes essential skin lipids with ceramides, cholesterol, and fatty acids • Supports healthy skin barrier function • Improves the appearance of skin fullness, smoothness, and radiance • Minimizes the appearance of pores • Increases skin’s tolerance to prescription retinoids • Lightweight, fast-absorbing formula • Paraben-, alcohol-, dye-, fragrance-, and gluten-free
Improves tightness, discomfort, and rough texture • Ceramides 1 & 3 are human-identical, and work synergistically to rebuild the moisture barrier • The only cholesterol dominant product on the market Did you know? This product is used to decrease side effects from drying prescriptions like Accutane, tretinoin, and benzoyl peroxide.
AQUA / WATER / EAU • DIMETHICONE • HYDROGENATED POLYISOBUTENE • GLYCERIN • CHOLESTEROL • C12-15 ALKYL BENZOATE • CERAMIDE 3 • HELIANTHUS ANNUUS SEED OIL UNSAPONIFIABLES / SUNFLOWER SEED OIL • UNSAPONIFIABLES • BIS-PEG-18 METHYL ETHER DIMETHYL SILANE • SODIUM POLYACRYLATE • PEG-10 DIMETHICONE • NYLON-12 • LAURYL PEG-9 POLYDIMETHYLSILOXYETHYL DIMETHICONE • DIMETHICONE/PEG-10/15 CROSSPOLYMERPHENOXYETHANOL • DISTEARDIMONIUM HECTORITE • HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID • AMMONIUM POLYACRYLOYLDIMETHYL TAURATE • CHLORPHENESIN • CAPRYLYL GLYCOL • PEG/PPG-18/18 DIMETHICONE • PROPYLENE CARBONATE • DISODIUM EDTA • ACRYLONITRILE/METHYL METHACRYLATE/VINYLIDENE CHLORIDE • COPOLYMER • ADENOSINE • DIPROPYLENE GLYCOL • LAVANDULA ANGUSTIFOLIA OIL / LAVENDER OIL • ROSMARINUS OFFICINALIS LEAF OIL / ROSEMARY LEAF OIL • T-BUTYL ALCOHOL • MENTHA PIPERITA OIL / PEPPERMINT OIL • SODIUM CITRATE • LINALOOL • ISOBUTANE • CERAMIDE EOP • BHT • TOCOPHEROL • LIMONENE
Before / After
*Average results shown. A dermatologist-controlled 8-week clinical study on 55 subjects with twice daily application of Triple Lipid Restore 2:4:2. Subjects also used SkinCeuticals Gentle Cleanser and Ultimate UV Defense SPF 30. Inclusion Criteria: Females ages 55-75 with moderate fi ne lines/wrinkles, uneven skin tone, skin dullness, skin roughness, lack of skin tone clarity, and lack of skin firmness.
**Average results shown. Lipidomics analysis (N=28 females aged 55-75). Statistically significant increase in lipids determined by spectrometric analysis of tape strips collected at baseline and after 8 weeks of twice daily application of Triple Lipid Restore 2:4:2.


Why this house
Antioxidant serums, advanced UV protection, corrective treatments. SkinCeuticals formulates every product on the basis of dermatological research.

From the House
Triple Lipid Restore 2:4:2 rebuilds the skin barrier with a precise ratio (2% ceramides, 4% cholesterol, 2% fatty acids) that mimics the natural proportions of skin. Rich cream texture, applied morning and night as the finishing step. The treatment to recommend for skin that no longer holds hydration despite usual creams. Felt effect from the first week, barrier structure restored after four to six weeks of continuous use.
From the same ritual
Atelier letter
New protocols, ingredients dissected, limited capsules, cabinet appointments. At the house’s own pace.